Solutions for Small Molecule Pharmaceutical Applications

Interested in our products and services? Learn More

Since 2001, Freeslate has delivered high throughput systems to over 50 pharmaceutical companies worldwide enabling them to overcome the issues of the traditional drug development process. Freeslate’s high throughput systems are designed to accelerate the development of drug candidates, enabling development scientists to get more information faster, using less material and reagents. Freeslate offers end-to-end solutions based on the Core Module 3 (CM3) platform and more targeted systems based on the smaller CM Protégé platform. The entire experimental process is supported from intuitive experimental design, to full automation of the experiments, to the integration of analytical tools and data for faster, better development decisions. By enabling scientists to run more experiments in parallel, a much larger experimental space can be explored, leading to shortened experiment cycles and superior development decisions.

Preformulation

Optimal “druggability” depends on a combination of factors such as compound solubility, crystallization, polymorphism, and salt selection. By systematically exploring a broad set of these factors during preformulation, a design space can be established that enables the rapid identification of optimal formulation parameters. Freeslate’s systems completely automate crystallization, polymorph, salt selection, and solubility screens to rapidly characterize the physicochemical properties of therapeutic candidates in a rapid and thorough manner.

Process Chemistry

The Freeslate Reaction Screening System screens substrates, catalysts, reactants, solvents, and reaction conditions for a wide range of organic transformations in a high throughput manner. Using the system, drug development researchers can screen hundreds of reaction conditions a day to explore new synthetic routes, optimize reaction yield and/or optical purity, reduce/eliminate impurities, identify alternate reaction conditions to reduce costs, identify a suitable solvent, or overcome IP issues. Because of the greater throughput, you can explore reaction parameters outside those used in conventional experimentation, reducing development risk and allowing for non-intuitive discoveries.

Managed Research Services

Outsourcing some of your laboratory’s work to Freeslate can accelerate your R&D efforts. Through our small molecule Managed Research Services, Freeslate can provide contract research services to support your drug development needs. Some examples of services Freeslate can provide include:

  • Solubility Screening
  • Crystal Form Screening (salt-selection and polymorph)
  • Chiral Resolution Screening
  • Ternary Phase Diagram
  • Reaction Optimization

Our Managed Research Services team is currently engaged with several major pharmaceutical companies and collaborating with them to achieve their development objectives. All work is performed using the same workflows we have successfully delivered to leading pharmaceutical and biotechnology companies worldwide.

Close

Login Success

You have successfully logged in to Freeslate.com.

New Account Has Been Created

A confirmation email will be sent to the email address you used to register. To complete the registration process, you must click the link in the email. You will be directed back to the Freeslate website.

Please re-enter your email address to download this content.

Thank you for your interest in Freeslate.
To download, please complete the form below.



Privacy Policy

Freeslate values your privacy and will not share your contact information for any reason without your consent.

Forgot Password

Please enter the email address currently on record for your account. A message will be sent to that address with further instructions on how to obtain a new password.


Reset Password

Please enter in a new password and verification below to create a new password for your account


Reset Password Error

An error has occured resetting your password. Please try again by entering in a new password below.


Reset Password - Email Sent

An email has been sent to you with instructions on how to continue resetting your Freeslate.com password.

Password Successfully Reset

Your password has been successfully reset. You may login below using your new credentials.

Reset Password - Error

Your email does not currently reside within our system or an error has occured. Please resubmit and try again.